如果您對該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: NFKBIA Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
NFKBIA Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。NFKBIA Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
NFKBIA Antibody
的詳細(xì)介紹
NFKBIA AntibodyProduct Profile
|
Product Name
|
Rabbit anti-NFKBIA Antibody - N-terminal region
|
|
Antibody Type
|
Primary Antibodies
|
|
Immunogen
|
The immunogen for Anti-NFKBIA antibody is: synthetic peptide directed towards the N-terminal region of Human NFKBIA
|
NFKBIA AntibodyKey Feature
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Host Species
|
Rabbit
|
|
Tested Applications
|
WB
|
|
Species Reactivity
|
Human
|
|
Concentration
|
1mg/ml
|
|
Purification
|
Affinity purified
|
NFKBIA AntibodyTarget Information
|
Gene Symbol
|
NFKBIA
|
|
Gene Synonyms
|
IKBA
MAD-3
NFKBI
|
|
Gene Summary
|
NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).
More
|
|
Alternative Names
|
IKBA
MAD-3
NFKBI
|
|
Molecular Weight(MW)
|
35kDa
|
|
Sequence
|
317 amino acids
|
NFKBIA AntibodyDatabase Links
|
Entrez Gene
|
4792
|
|
SwissProt ID
|
P25963
|
|
Protein Accession
|
NP_065390
|
NFKBIA AntibodyApplication
-
Western blot
Host: Rabbit
Target Name: NFKBIA
Sample Tissue: Hela Whole Cell lysates
Antibody Dilution: 1.0ug/ml
Additional Information
|
Form
|
Liquid
|
|
Storage Instructions
|
Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
|
|
Storage Buffer
|
phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
|
