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產(chǎn)品名稱(chēng): SSRP1 antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
SSRP1 antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。SSRP1 antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
SSRP1 antibody
的詳細(xì)介紹
SSRP1 antibodyProduct Profile
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Product Name
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Rabbit anti-SSRP1 polyclonal antibody - middle region
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Antibody Type
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Primary Antibodies
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Immunogen
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The immunogen for anti-SSRP1 antibody: synthetic peptide directed towards the middle region of human SSRP1
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SSRP1 antibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Species Reactivity
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BovineGuinea PigHorseHumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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SSRP1 antibodyTarget Information
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Gene Symbol
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SSRP1
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Gene Synonyms
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FACT
FACT80
T160
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Gene Full Name
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Structure specific recognition protein 1
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Gene Summary
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SSRP1 is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. SSRP1 contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. It also functions as a co-activator of the transcriptional activator p63. The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
More
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Alternative Names
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FACT
FACT80
T160
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Molecular Weight(MW)
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81kDa
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Sequence
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709 amino acids
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SSRP1 antibodyDatabase Links
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Entrez Gene
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6749
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SwissProt ID
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Q08945
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Protein Accession
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NP_003137
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SSRP1 antibodyApplication
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Western blot
0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: OVCAR-3 cell lysate
Additional Information
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Form
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Liquid
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Storage Instructions
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Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
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Storage Buffer
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phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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