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產(chǎn)品名稱: CREBL1 antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
CREBL1 antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。CREBL1 antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
CREBL1 antibody
的詳細(xì)介紹
CREBL1 antibodyProduct Profile
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Product Name
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Rabbit anti-CREBL1 polyclonal antibody - middle region
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Antibody Type
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Primary Antibodies
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Immunogen
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The immunogen for anti-CREBL1 antibody: synthetic peptide directed towards the middle region of human CREBL1
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CREBL1 antibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Species Reactivity
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Pig
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Concentration
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1mg/ml
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Purification
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Affinity purified
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CREBL1 antibodyTarget Information
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Gene Symbol
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CREBL1
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Gene Synonyms
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CREB-RP
FLJ10066
G13
CREBL1
More
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Gene Full Name
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Activating transcription factor 6 beta
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Gene Summary
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ATF6B(CREBL1) is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. ATF6B is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene bears sequence similarity with the Creb/ATF subfamily of the bZip superfamily of transcription factors. It localizes to both the cytoplasm and the nucleus. The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
More
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Alternative Names
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CREB-RP
FLJ10066
G13
CREBL1
More
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Molecular Weight(MW)
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77kDa
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Sequence
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703 amino acids
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CREBL1 antibodyDatabase Links
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Entrez Gene
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1388
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SwissProt ID
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Q99941
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Protein Accession
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NP_004372
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CREBL1 antibodyApplication
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Western blot
0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human Muscle
Additional Information
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Form
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Liquid
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Storage Instructions
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Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
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Storage Buffer
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phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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