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產(chǎn)品名稱: IRF6 antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
IRF6 antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。IRF6 antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
IRF6 antibody
的詳細(xì)介紹
IRF6 antibodyProduct Profile
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Product Name
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Rabbit anti-IRF6 polyclonal antibody - middle region
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Antibody Type
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Primary Antibodies
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Immunogen
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The immunogen for anti-IRF6 antibody: synthetic peptide directed towards the middle region of human IRF6
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IRF6 antibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WBIHC
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Species Reactivity
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BovineDogHorseHumanMousePigRabbitRatSheepZebra Fish
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Concentration
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1mg/ml
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Purification
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Affinity purified
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IRF6 antibodyTarget Information
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Gene Symbol
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IRF6
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Gene Synonyms
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LPS
OFC6
PIT
PPS
VWS
VWS1
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Gene Full Name
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Interferon regulatory factor 6
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Gene Summary
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IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
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Alternative Names
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LPS
OFC6
PIT
PPS
VWS
VWS1
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Molecular Weight(MW)
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53kDa
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Sequence
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467 amino acids
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IRF6 antibodyDatabase Links
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Entrez Gene
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3664
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SwissProt ID
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O14896
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Protein Accession
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NP_006138
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IRF6 antibodyApplication
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Immunohistochemistry
Immunohistochemistry with Placenta tissue at an antibody concentration of 5ug/ml using anti-IRF6 antibody
Additional Information
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Form
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Liquid
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Storage Instructions
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Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
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Storage Buffer
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phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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