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SMAD4 antibody

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產(chǎn)品名稱: SMAD4 antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔

簡(jiǎn)單介紹

SMAD4 antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。SMAD4 antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。


SMAD4 antibody  的詳細(xì)介紹

SMAD4 antibodyProduct Profile

Product Name Rabbit anti-SMAD4 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Immunogen 
The immunogen for anti-SMAD4 antibody: synthetic peptide directed towards the middle region of human SMAD4

SMAD4 antibodyKey Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

Species Reactivity

BovineGoatGuinea PigHorseHumanMousePigRat

Concentration 1mg/ml
Purification Protein A

SMAD4 antibodyTarget Information

Gene Symbol SMAD4
Gene Synonyms
JIP
DPC4
MADH4
MYHRS
More 
Gene Full Name SMAD family member 4
Gene Summary
SMAD4 is one of the Smad family members, which are essential intracellular signalling components of the transforming growth factor-beta (TGF-beta) superfamily. Smad2 and Smad3 are structurally highly similar and mediate TGF-beta signals. Smad4 is distantly related to Smads 2 and 3, and forms a heteromeric complex with Smad2 after TGF-beta or activin stimulation. TGF-beta induces heteromeric complexes of Smads 2, 3 and 4, and their concomitant translocation to the nucleus, which is required for efficient TGF-beta signal transduction
More 
Alternative Names
JIP
DPC4
MADH4
MYHRS
More 
Molecular Weight(MW) 60kDa
Sequence 552 amino acids

SMAD4 antibodyDatabase Links

Entrez Gene 4089
SwissProt ID Q13485
Protein Accession NP_005350

SMAD4 antibodyApplication

  • Western blot

    SMAD4 antibody - middle region validated by WB using U2OS nuclear extracts

  • Western blot

    Sample Type: Human nuclear cell extracts (30ug)
    Primary Dilution: 1:1000
    Secondary Antibody: anti-Rabbit HRP
    Secondary Dilution: 1:20000
    Image Submitted By:  Katarina Luciakova
    Cancer Research Institute See Customer Feedback tab for detailed information.

  • Western blot

    1.25ug/ml
    ELISA Titer: 1:312500
    Positive Control: HepG2 cell lysate

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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