Estrogen Receptor a (phospho Ser118) Antibody
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產(chǎn)品名稱: Estrogen Receptor a (phospho Ser118) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關文檔
簡單介紹
Estrogen Receptor a (phospho Ser118) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Estrogen Receptor a (phospho Ser118) Antibody嚴格的質量控制和驗證實驗包括各種不同的應用：WB、細胞**熒光、**組化、流式細胞術、ELISA、CHIP、IP和peptide array。
Estrogen Receptor a (phospho Ser118) Antibody
的詳細介紹
Estrogen Receptor a (phospho Ser118) AntibodyProduct Profile
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Product Name
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Estrogen Receptor a (phospho Ser118) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.1) Ramsauer VP, et al. (2003) J Biol Chem; 278 (32): 30142-7. Jepson S, et al. (2002) Oncogene; 21 (49): 7524-32. Ren Z, et al. (2002) J Biol Chem; 277 (41): 38486-93. Eppenberger-Castori S, et al. (2001) J Clin Oncol; 19 (3): 645-56.
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Immunogen
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Estrogen Receptor-a (Phospho-Ser118) antibody was raised against a peptide sequence around phosphorylation site of serine 118 (Q-L-S (p) -P-F) derived from Human Estrogen Receptor-α.
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Estrogen Receptor a (phospho Ser118) AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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IFIHCWB
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:
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Species Reactivity
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HumanMouse
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Estrogen Receptor a (phospho Ser118) AntibodyTarget Information
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Gene Symbol
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ESR1
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Alternative Names
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ER
ESR
Era
ESRA
ESTRR
NR3A1
BBC6
BCL2L8
ER
ESR1
ESTR
ESTRA
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Molecular Weight(MW)
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66 kDa
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Tissue Specificity
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This antibody detects endogenous level of Estrogen Receptor-αonly when phosphorylated at serine 118.
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Estrogen Receptor a (phospho Ser118) AntibodyDatabase Links
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Entrez Gene
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2099
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Protein Accession
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NP_000116.2
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Estrogen Receptor a (phospho Ser118) AntibodyApplication
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Application
Top Image: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Estrogen Receptor-α (Phospho-Ser118). Bottom Image: Immunofluorescence staining of methanol-fixed MCF cells using Estrogen Receptor-α (Phospho-Ser118).
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Application
Western blot analysis of lysed extracts from MDA cells untreated or treated with Estradiol using Estrogen Receptor-α (Phospho-Ser118).
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Application Notes
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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