p70 S6 Kinase (phospho Ser411) Antibody
如果您對(duì)該產(chǎn)品感興趣的話(huà),可以
產(chǎn)品名稱(chēng): p70 S6 Kinase (phospho Ser411) Antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
p70 S6 Kinase (phospho Ser411) Antibody迅速增長(zhǎng)的產(chǎn)品線(xiàn)包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。p70 S6 Kinase (phospho Ser411) Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
p70 S6 Kinase (phospho Ser411) Antibody
的詳細(xì)介紹
p70 S6 Kinase (phospho Ser411) AntibodyProduct Profile
|
Product Name
|
p70 S6 Kinase (phospho Ser411) Antibody
|
|
Antibody Type
|
Primary Antibodies
|
|
Product description
|
Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.1) Satoru Eguchi et al. (1999) J Biol Chem, Vol. 274: 36843-36851Papst PJ, et al. (1998) J Biol Chem. 273 (24): 15077-84. Ulrike Krause et al. (2002) Eur. J. Biochem. 269: 3751-3759 cLe, X. F, et al. (2003) Oncogene 22: 484–97
More
|
|
Immunogen
|
p70 S6 Kinase (Phospho-Ser411) antibody was raised against a peptide sequence around phosphorylation site of serine 411 (I-R-S (p) -P-R) derived from Human p70 S6 Kinase.
|
p70 S6 Kinase (phospho Ser411) AntibodyKey Feature
|
Clonality
|
Polyclonal
|
|
Host Species
|
Rabbit
|
|
Species Reactivity
|
Human
|
|
Concentration
|
1mg/ml
|
|
Purification
|
Affinity purified
|
p70 S6 Kinase (phospho Ser411) AntibodyTarget Information
|
Gene Symbol
|
RPS6KB1
|
|
Alternative Names
|
S6K
PS6K
S6K1
STK14A
p70-S6K
p70S6KA
p70-alpha
S6K-beta-1
p70(S6K)-alpha
MACS
PRKCSL
KS6B1
P70-S6K
RPS6KB1
S6K
More
|
|
Molecular Weight(MW)
|
70 85 kDa
|
|
Tissue Specificity
|
This antibody detects endogenous level of p70 S6 Kinase only when phosphorylated at serine 411.
|
p70 S6 Kinase (phospho Ser411) AntibodyDatabase Links
|
Entrez Gene
|
6198
|
|
Protein Accession
|
NP_003152.1
|
p70 S6 Kinase (phospho Ser411) AntibodyApplication
-
Application
Top Image: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p70 S6 Kinase (Phospho-Ser411). Bottom Image: Immunofluorescence staining of methanol-fixed MCF7 cells using p70 S6 Kinase (Phospho-Ser411).
-
Application
Western blot analysis of lysed extracts from MCF cells untreated or treated with EGF using p70 S6 Kinase (Phospho-Ser411).
|
Application Notes
|
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:
|
Additional Information
|
Form
|
Liquid
|
|
Storage Instructions
|
Store antibody at -20?C for up to one year.
|
|
Storage Buffer
|
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
|