如果您對(duì)該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱(chēng): NFKB1 Antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
NFKB1 Antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。NFKB1 Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
NFKB1 Antibody
的詳細(xì)介紹
NFKB1 AntibodyProduct Profile
|
Product Name
|
NFKB1 Antibody
|
|
Antibody Type
|
Primary Antibodies
|
|
Product description
|
NFKB1 is a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth.1) Legembre, P., et al., J. Biol. Chem. 279(45):46742-46747 (2004).
More
|
|
Immunogen
|
This NFKB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 911-939 amino acids from human NFKB1.
|
NFKB1 AntibodyKey Feature
|
Clonality
|
Polyclonal
|
|
Isotype
|
Ig
|
|
Host Species
|
Rabbit
|
|
Tested Applications
|
WB
|
|
|
For WB starting dilution is: 1:1000:
|
|
Species Reactivity
|
Human
|
|
Concentration
|
1mg/ml
|
|
Purification
|
Affinity purified
|
NFKB1 AntibodyTarget Information
|
Gene Symbol
|
NFKB1
|
|
Alternative Names
|
Nuclear factor NF-kappa-B p105 subunit
DNA-binding factor KBF1
EBP-1
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Nuclear factor NF-kappa-B p50 subunit
NFKB1
More
|
|
Molecular Weight(MW)
|
105 kDa
|
|
Sequence Similarities
|
Predicted species reactivity based on immunogen sequence: Chicken
|
NFKB1 AntibodyDatabase Links
|
Entrez Gene
|
4790
|
|
Protein Accession
|
P19838
|
NFKB1 AntibodyApplication
-
Application
Western Blot at 1:1000 dilution Lane 1: Raji whole cell lysate Lane 2: A431 whole cell lysate Lysates/proteins at 20 ug per lane.
|
Application Notes
|
For WB starting dilution is: 1:1000:
|
Additional Information
|
Form
|
Liquid
|
|
Storage Instructions
|
Store at 4?C for three months and -20?C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
|
|
Storage Buffer
|
Supplied in PBS with 0.09% (W/V) sodium azide.
|