HER2 (phospho Tyr877) Antibody
如果您對該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: HER2 (phospho Tyr877) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
HER2 (phospho Tyr877) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。HER2 (phospho Tyr877) Antibody嚴格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細胞**熒光、**組化、流式細胞術(shù)、ELISA、CHIP、IP和peptide array。
HER2 (phospho Tyr877) Antibody
的詳細介紹
HER2 (phospho Tyr877) AntibodyProduct Profile
|
Product Name
|
HER2 (phospho Tyr877) Antibody
|
|
Antibody Type
|
Primary Antibodies
|
|
Product description
|
Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-alpha and amphiregulin.1) Dittadi, R. et al. (2000) J. Natl. Cancer Inst. 92, 1443-1444. Muthuswamy, S. K. et al. (1999) Mol. Cell. Biol. 19, 6845-6857. Qian, X. et al. (1994) Proc. Natl. Acad. Sci. USA 91, 1500-1504.
More
|
|
Immunogen
|
HER2 (Phospho-Tyr877) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 877 (T-E-Y (p) -H-A) derived from Human HER2.
|
HER2 (phospho Tyr877) AntibodyKey Feature
|
Clonality
|
Polyclonal
|
|
Host Species
|
Rabbit
|
|
Tested Applications
|
IFIHCWB
|
|
|
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:
|
|
Species Reactivity
|
HumanMouseRat
|
|
Concentration
|
1mg/ml
|
|
Purification
|
Affinity purified
|
HER2 (phospho Tyr877) AntibodyTarget Information
|
Gene Symbol
|
ERBB2
|
|
Alternative Names
|
NEU
NGL
HER2
TKR1
CD340
HER-2
MLN19
HER-2/neu
BHLHE39
C-erbB-2
ErbB2
More
|
|
Molecular Weight(MW)
|
185 kDa
|
|
Tissue Specificity
|
This antibody detects endogenous level of HER2 only when phosphorylated at tyrosine 877.
|
HER2 (phospho Tyr877) AntibodyDatabase Links
|
Entrez Gene
|
2064
|
|
Protein Accession
|
NP_001005862.1
|
HER2 (phospho Tyr877) AntibodyApplication
-
Application
Western blot analysis of lysed extracts from A431 cells untreated or treated with EGF using HER2 (Phospho-Tyr877).
-
Application
Top Image: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using HER2 (Phospho-Tyr877). Bottom Image: Immunofluorescence staining of methanol-fixed MCF7 cells using HER2 (Phospho-Tyr877).
|
Application Notes
|
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:
|
Additional Information
|
Form
|
Liquid
|
|
Storage Instructions
|
Store antibody at -20?C for up to one year.
|
|
Storage Buffer
|
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
|