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產(chǎn)品資料

P38 MAPK (phospho Thr180) Antibody

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產(chǎn)品名稱(chēng): P38 MAPK (phospho Thr180) Antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔

簡(jiǎn)單介紹

P38 MAPK (phospho Thr180) Antibody迅速增長(zhǎng)的產(chǎn)品線包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。P38 MAPK (phospho Thr180) Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用:WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。


P38 MAPK (phospho Thr180) Antibody  的詳細(xì)介紹

P38 MAPK (phospho Thr180) AntibodyProduct Profile

Product Name P38 MAPK (phospho Thr180) Antibody
Antibody Type Primary Antibodies
Product description
					
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.1) Kim JE, et al. (2005) J Proteome Res Jul-Aug; 4 (4): 1339-1346Meng F, et al. (2005) Am J Physiol Cell Physiol May 25Jin ZH, et al. (2005) Oncogene Mar 17; 24 (12): 1973-1981
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Immunogen
P38 MAPK (Phospho-Thr180) antibody was raised against a peptide sequence around phosphorylation site of threonine 180 (E-M-T (p) -G-Y ) derived from Human P38MAPK.

P38 MAPK (phospho Thr180) AntibodyKey Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IHCWB

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

P38 MAPK (phospho Thr180) AntibodyTarget Information

Gene Symbol MAPK14
Alternative Names
RK
p38
CSBP
EXIP
Mxi2
CSBP1
CSBP2
CSPB1
PRKM14
PRKM15
SAPK2A
p38ALPHA
PLC1
MAPK2
MAPKAPK-2
MAPKAPK2
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Molecular Weight(MW) 43 kDa
Tissue Specificity This antibody detects endogenous level of P38 MAPK only when phosphorylated at Threonine 180.

P38 MAPK (phospho Thr180) AntibodyDatabase Links

Entrez Gene 1432
Protein Accession NP_001306.1

P38 MAPK (phospho Thr180) AntibodyApplication

  • Application

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using P38 MAPK (Phospho-Thr180).

  • Application

    Western blot analysis of lysed extracts from HT29 cells untreated or treated with UV using P38 MAPK (Phospho-Thr180).

Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20?C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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