VEGFR2 (phospho Tyr951) Antibody
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產(chǎn)品名稱: VEGFR2 (phospho Tyr951) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
VEGFR2 (phospho Tyr951) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。VEGFR2 (phospho Tyr951) Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
VEGFR2 (phospho Tyr951) Antibody
的詳細(xì)介紹
VEGFR2 (phospho Tyr951) AntibodyProduct Profile
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Product Name
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VEGFR2 (phospho Tyr951) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions1) Zeng H, et al. (2001) J Biol Chem. 276 (35): 32714-32719. Dougher M, et al. (1999) Oncogene. 18 (8): 1619-1627.
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Immunogen
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VEGFR2 (Phospho-Tyr951) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 951 (K-D-Y (p) -V-G) derived from Human VEGFR2.
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VEGFR2 (phospho Tyr951) AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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IFIHCWB
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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VEGFR2 (phospho Tyr951) AntibodyTarget Information
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Gene Symbol
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KDR
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Alternative Names
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FLK1
CD309
VEGFR
VEGFR2
HER3
FLK1
KDR
VGFR2
VGR2
kinase insert domain receptor
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Molecular Weight(MW)
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230 kDa
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Tissue Specificity
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This antibody detects endogenous level of VEGFR2 only when phosphorylated at tyrosine 951.
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VEGFR2 (phospho Tyr951) AntibodyDatabase Links
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Entrez Gene
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3791
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Protein Accession
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NP_002244.1
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VEGFR2 (phospho Tyr951) AntibodyApplication
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Application
Western blot analysis of lysed extracts from G-CSF-treated HUVEC and serum-treated HT29 cells using VEGFR2 (Phospho-Tyr951).
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Application
Top Image: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using VEGFR2 (Phospho-Tyr951). Bottom Image: Immunofluorescence staining of methanol-fixed MCF7 cells using VEGFR2 (Phospho-Tyr951).
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Application Notes
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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