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產(chǎn)品資料

Smad3 (phospho Thr179) Antibody

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產(chǎn)品名稱: Smad3 (phospho Thr179) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔

簡單介紹

Smad3 (phospho Thr179) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Smad3 (phospho Thr179) Antibody嚴格的質(zhì)量控制和驗證實驗包括各種不同的應用:WB、細胞**熒光、**組化、流式細胞術(shù)、ELISA、CHIP、IP和peptide array。


Smad3 (phospho Thr179) Antibody  的詳細介紹

Smad3 (phospho Thr179) AntibodyProduct Profile

Product Name Smad3 (phospho Thr179) Antibody
Antibody Type Primary Antibodies
Product description
					
Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.1) Cohen-Solal KA, et al. (2011) Pigment Cell Melanoma Res 24, 512-24
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Immunogen
Smad3 (phospho Thr179) antibody was raised against a peptide sequence around phosphorylation site of threonine179 (P-E-T (p)-P-P) derived from Human Smad3 .

Smad3 (phospho Thr179) AntibodyKey Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

Western Blot: 1:500~1:1000:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Smad3 (phospho Thr179) AntibodyTarget Information

Gene Symbol SMAD3
Alternative Names
JV15-2
MAD-3
MADH3
Smad 3
Mothers against decapentaplegic homolog 3
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Molecular Weight(MW) 50 kDa
Tissue Specificity The antibody detects endogenous level of Smad3 only when phosphorylated at threonine 179.

Smad3 (phospho Thr179) AntibodyDatabase Links

Entrez Gene 4088
Protein Accession NP_001138574.1

Smad3 (phospho Thr179) AntibodyApplication

  • Application

    Western blot analysis of extracts from HeLa cells treated with TNF using Phospho-Smad3 (Thr179) Antibody. The lane on the right is treated with the antigen-specific peptide.

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20?C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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