Smad3 (phospho Ser425) Antibody
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產(chǎn)品名稱: Smad3 (phospho Ser425) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Smad3 (phospho Ser425) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Smad3 (phospho Ser425) Antibody嚴格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細胞**熒光、**組化、流式細胞術(shù)、ELISA、CHIP、IP和peptide array。
Smad3 (phospho Ser425) Antibody
的詳細介紹
Smad3 (phospho Ser425) AntibodyProduct Profile
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Product Name
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Smad3 (phospho Ser425) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.1) Shi W, et al. J Cell Sci. 2007 Apr 1;120 (Pt 7): 1216-24Seong HA, et al. J Biol Chem. 2007 Apr 20;282 (16): 12272-89Wordinger RJ, et al. Invest Ophthalmol Vis Sci. 2007 Mar;48 (3): 1191-200LeClair RJ, et al. Circ Res. 2007 Mar 30;100 (6): 826-33
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Immunogen
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Smad3 (Phospho-Ser425) antibody was raised against a peptide sequence around phosphorylation site of serine 425 (C-S-S-V-S (p) ) derived from Human Smad3.
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Smad3 (phospho Ser425) AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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IHC
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, Immunohistochemistry: 1:50~1:100:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Smad3 (phospho Ser425) AntibodyTarget Information
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Gene Symbol
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SMAD3
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Alternative Names
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LDS3
LDS1C
MADH3
JV15-2
HSPC193
HsT17436
PTP2C
SHPTP2
MAD-3
Mad3
Mothers against DPP homolog 3
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Molecular Weight(MW)
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52 kDa
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Tissue Specificity
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This antibody detects endogenous level of Smad3 only when phosphorylated at serine 425.
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Smad3 (phospho Ser425) AntibodyDatabase Links
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Entrez Gene
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4088
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Protein Accession
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NP_001138574.1
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Smad3 (phospho Ser425) AntibodyApplication
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Application
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Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Smad3 (Phospho-Ser425).
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Application Notes
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, Immunohistochemistry: 1:50~1:100:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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