MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. More
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MUC1.
ELISAIHCWB
Human
Antibody used in IHC on Human stomach at 1:500.
Antibody used in IHC on Pig stomach at 1:500.
Antibody used in WB on Human Jurkat 2.5 ug/ml.
Antibody used in IHC on Human Kidney at 4.0-8.0 ug/ml.