IGF1R (phospho Tyr1346) Antibody
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產(chǎn)品名稱: IGF1R (phospho Tyr1346) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
IGF1R (phospho Tyr1346) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。IGF1R (phospho Tyr1346) Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
IGF1R (phospho Tyr1346) Antibody
的詳細(xì)介紹
IGF1R (phospho Tyr1346) AntibodyProduct Profile
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Product Name
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IGF1R (phospho Tyr1346) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.1) Ullrich A., EMBO J. 5:2503-2512(1986).
More
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Immunogen
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IGF1R (phospho Tyr1346) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1346 (Q-P-Y (p)-A-H) derived from Human IGF1R .
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IGF1R (phospho Tyr1346) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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IHC
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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IGF1R (phospho Tyr1346) AntibodyTarget Information
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Gene Symbol
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IGF1R
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Alternative Names
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CD221
kinase IGF1R
IGF1R
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Molecular Weight(MW)
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154 kDa
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Tissue Specificity
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The antibody detects endogenous levels of IGF1R only when phosphorylated at tyrosine 1346.
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IGF1R (phospho Tyr1346) AntibodyDatabase Links
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Entrez Gene
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3480
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Protein Accession
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NP_000866.1
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IGF1R (phospho Tyr1346) AntibodyApplication
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Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using IGF1R (Phospho-Tyr1346) antibody (left) or the same antibody preincubated with blocking peptide (right).
Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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