如果您對該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: IGF1 Receptor Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
IGF1 Receptor Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。IGF1 Receptor Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用:WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
IGF1 Receptor Antibody
的詳細(xì)介紹
IGF1 Receptor AntibodyProduct Profile
Product Name
|
IGF1 Receptor Antibody
|
Antibody Type
|
Primary Antibodies
|
Product description
|
The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.1) Song, R.X., et al., Proc. Natl. Acad. Sci. U.S.A. 101(7):2076-2081 (2004).
More
|
Immunogen
|
This IGF1 Receptor (IGF1R) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-51 amino acids from the N-terminal region of human IGF1 Receptor (IGF1R).
|
IGF1 Receptor AntibodyKey Feature
Clonality
|
Polyclonal
|
Isotype
|
Ig
|
Host Species
|
Rabbit
|
Tested Applications
|
IHC-PWB
|
|
For WB starting dilution is: 1:2000 For IHC-P starting dilution is: 1:50~100:
|
Species Reactivity
|
Human
|
Concentration
|
1mg/ml
|
Purification
|
Unpurified
|
IGF1 Receptor AntibodyTarget Information
Gene Symbol
|
IGF1R
|
Alternative Names
|
Insulin-like growth factor 1 receptor
Insulin-like growth factor I receptor
IGF-I receptor
CD221
Insulin-like growth factor 1 receptor alpha chain
Insulin-like growth factor 1 receptor beta chain
IGF1R
More
|
Molecular Weight(MW)
|
155 kDa
|
Sequence Similarities
|
Predicted species reactivity based on immunogen sequence: Mouse
|
IGF1 Receptor AntibodyDatabase Links
Entrez Gene
|
3480
|
Protein Accession
|
P08069
|
IGF1 Receptor AntibodyApplication
-
Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma.
-
Application
Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: A549 whole cell lysate Lysates/proteins at 20 ug per lane.
Application Notes
|
For WB starting dilution is: 1:2000 For IHC-P starting dilution is: 1:50~100:
|
Additional Information
Form
|
Liquid
|
Storage Instructions
|
Store at 4?C for three months and -20?C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
|
Storage Buffer
|
Supplied in PBS with 0.09% (W/V) sodium azide.
|