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產(chǎn)品資料

IGF1 Receptor Antibody

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產(chǎn)品名稱: IGF1 Receptor Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔

簡單介紹

IGF1 Receptor Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。IGF1 Receptor Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用:WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。


IGF1 Receptor Antibody  的詳細(xì)介紹

IGF1 Receptor AntibodyProduct Profile

Product Name IGF1 Receptor Antibody
Antibody Type Primary Antibodies
Product description
					
The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.1) Song, R.X., et al., Proc. Natl. Acad. Sci. U.S.A. 101(7):2076-2081 (2004).
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Immunogen
This IGF1 Receptor (IGF1R) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-51 amino acids from the N-terminal region of human IGF1 Receptor (IGF1R).

IGF1 Receptor AntibodyKey Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

IHC-PWB

For WB starting dilution is: 1:2000 For IHC-P starting dilution is: 1:50~100:
Species Reactivity

Human

Concentration 1mg/ml
Purification Unpurified

IGF1 Receptor AntibodyTarget Information

Gene Symbol IGF1R
Alternative Names
Insulin-like growth factor 1 receptor
Insulin-like growth factor I receptor
IGF-I receptor
CD221
Insulin-like growth factor 1 receptor alpha chain
Insulin-like growth factor 1 receptor beta chain
IGF1R
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Molecular Weight(MW) 155 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Mouse

IGF1 Receptor AntibodyDatabase Links

Entrez Gene 3480
Protein Accession P08069

IGF1 Receptor AntibodyApplication

  • Application

    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma.

  • Application

    Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: A549 whole cell lysate Lysates/proteins at 20 ug per lane.

Application Notes
For WB starting dilution is: 1:2000 For IHC-P starting dilution is: 1:50~100:

Additional Information

Form Liquid
Storage Instructions Store at 4?C for three months and -20?C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.

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