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產(chǎn)品資料

IGF 1R Antibody

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產(chǎn)品名稱: IGF 1R Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔

簡單介紹

IGF 1R Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。IGF 1R Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用:WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。


IGF 1R Antibody  的詳細(xì)介紹

IGF 1R AntibodyProduct Profile

Product Name IGF 1R Antibody
Antibody Type Primary Antibodies
Product description
					
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.1) Adams, T. E. et al. (2000) Cell. Mol. Life Sci. 57, 1050-1093Baserga, R. et al. (2000) Oncogene 19, 5574-5581Scheidegger, K. J. et al. (2000) J. Biol. Chem. 275, 38921-38928. O'Connor R, et al. Mol Cell Biol 1997 Jan; 17 (1): 427-35
Immunogen
IGF-1R (Ab-1346) antibody was raised against a peptide sequence around aa.1344~1348 (Q-P-Y-A-H) derived from Human IGF-1R .

IGF 1R AntibodyKey Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IHCWB

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

IGF 1R AntibodyTarget Information

Gene Symbol IGF1R
Alternative Names
IGFR
CD221
IGFIR
JTK13
BHLHA38
TWIST
Insulin-like growth factor I receptor
IGF1R
kinase IGF1R
Molecular Weight(MW) 200, 95 kDa
Tissue Specificity This antibody detects endogenous level of total IGF-1R protein.

IGF 1R AntibodyDatabase Links

Entrez Gene 3480
Protein Accession NP_000866.1

IGF 1R AntibodyApplication

  • Application

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IGF-1R (Ab-1346).

  • Application

    Western blot analysis of lysed extracts from 293 cells using IGF-1R (Ab-1346).

Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20?C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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