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產(chǎn)品名稱: IGF 1R Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
IGF 1R Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。IGF 1R Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
IGF 1R Antibody
的詳細(xì)介紹
IGF 1R AntibodyProduct Profile
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Product Name
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IGF 1R Antibody
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Antibody Type
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Primary Antibodies
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Product description
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This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.1) Adams, T. E. et al. (2000) Cell. Mol. Life Sci. 57, 1050-1093Baserga, R. et al. (2000) Oncogene 19, 5574-5581Scheidegger, K. J. et al. (2000) J. Biol. Chem. 275, 38921-38928. O'Connor R, et al. Mol Cell Biol 1997 Jan; 17 (1): 427-35
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Immunogen
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IGF-1R (Ab-1346) antibody was raised against a peptide sequence around aa.1344~1348 (Q-P-Y-A-H) derived from Human IGF-1R .
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IGF 1R AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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IHCWB
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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IGF 1R AntibodyTarget Information
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Gene Symbol
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IGF1R
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Alternative Names
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IGFR
CD221
IGFIR
JTK13
BHLHA38
TWIST
Insulin-like growth factor I receptor
IGF1R
kinase IGF1R
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Molecular Weight(MW)
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200, 95 kDa
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Tissue Specificity
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This antibody detects endogenous level of total IGF-1R protein.
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IGF 1R AntibodyDatabase Links
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Entrez Gene
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3480
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Protein Accession
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NP_000866.1
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IGF 1R AntibodyApplication
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Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IGF-1R (Ab-1346).
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Application
Western blot analysis of lysed extracts from 293 cells using IGF-1R (Ab-1346).
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Application Notes
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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