Smad2 (phospho Thr220) Antibody
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產(chǎn)品名稱: Smad2 (phospho Thr220) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關文檔
簡單介紹
Smad2 (phospho Thr220) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Smad2 (phospho Thr220) Antibody嚴格的質量控制和驗證實驗包括各種不同的應用：WB、細胞**熒光、**組化、流式細胞術、ELISA、CHIP、IP和peptide array。
Smad2 (phospho Thr220) Antibody
的詳細介紹
Smad2 (phospho Thr220) AntibodyProduct Profile
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Product Name
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Smad2 (phospho Thr220) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.1) Sang Gyun Kim et al. (2004) Mol Biol Cell. February; 15 (2): 420–434. Rebecca A. Randall et al. (2004) Mol Cell Biol. February; 24 (3): 1106–1121. Kimberly A Brown et al. (2004) Breast Cancer Res. ; 6 (3): R215–R231.
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Immunogen
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Smad2 (Phospho-Thr220) antibody was raised against a peptide sequence around phosphorylation site of threonine 220 (P-E-T (p) -P-P) derived from Human Smad2.
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Smad2 (phospho Thr220) AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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WB
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Western Blot: 1:500~1:1000:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Smad2 (phospho Thr220) AntibodyTarget Information
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Gene Symbol
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SMAD2
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Alternative Names
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JV18
MADH2
MADR2
JV18-1
hMAD-2
hSMAD2
ERBB
ERBB1
HER1
Mad-related protein 2
Mothers against DPP homolog 2
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Molecular Weight(MW)
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60 kDa
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Tissue Specificity
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This antibody detects endogenous level of Smad2 only when phosphorylated at threonine 220.
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Smad2 (phospho Thr220) AntibodyDatabase Links
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Entrez Gene
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4087
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Protein Accession
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NP_001003652.1
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Smad2 (phospho Thr220) AntibodyApplication
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Application
Western blot analysis of lysed extracts from HeLa cells untreated or treated with PMA using Smad2 (Phospho-Thr220).
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Application Notes
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Western Blot: 1:500~1:1000:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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