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a Synuclein (phospho Ser129) Antibody

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產(chǎn)品名稱(chēng): a Synuclein (phospho Ser129) Antibody
產(chǎn)品型號(hào):
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無(wú)相關(guān)文檔

簡(jiǎn)單介紹

a Synuclein (phospho Ser129) Antibody迅速增長(zhǎng)的產(chǎn)品線(xiàn)包括一抗、二抗、**測(cè)定及細(xì)胞檢測(cè)試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。 a Synuclein (phospho Ser129) Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用:WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。


a Synuclein (phospho Ser129) Antibody  的詳細(xì)介紹

 a Synuclein (phospho Ser129) AntibodyProduct Profile

Product Name a Synuclein (phospho Ser129) Antibody
Antibody Type Primary Antibodies
Product description
					
May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.1) Takahashi T, et al. J Biol Chem 2003 Oct 24; 278 (43): 42225-33Ahn BH, et al. J Biol Chem 2002 Apr 05; 277 (14): 12334-42Negro A, et al. FASEB J 2002 Feb; 16 (2): 210-2Goldberg, et al. Nat. Cell Biol. 2000; 2, 115-119.
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Immunogen
a-Synuclein (Phospho-Ser129) antibody was raised against a peptide sequence around phosphorylation site of serine 129 (M-P-S (p) -E-E) derived from Human α-Synuclein.

 a Synuclein (phospho Ser129) AntibodyKey Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

WB

Western Blot: 1:500~1:1000:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

 a Synuclein (phospho Ser129) AntibodyTarget Information

Gene Symbol SNCA
Alternative Names
PD1
NACP
PARK1
PARK4
ERBB
ERBB1
HER1
SYN
SYUA
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Molecular Weight(MW) 18 kDa
Tissue Specificity This antibody detects endogenous level of VEGFR2 only when phosphorylated at tyrosine 1214.

 a Synuclein (phospho Ser129) AntibodyDatabase Links

Entrez Gene 6622
Protein Accession NP_000336.1

 a Synuclein (phospho Ser129) AntibodyApplication

  • Application

    Western blot analysis of lysed extracts from mouse brain tissue using α-Synuclein (Phospho-Ser129).

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20?C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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