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產(chǎn)品名稱: Amyloid-Beta 3 Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Amyloid-Beta 3 Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Amyloid-Beta 3 Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
Amyloid-Beta 3 Antibody
的詳細(xì)介紹
Amyloid-Beta 3 AntibodyProduct Profile
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Product Name
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Amyloid-Beta 3 Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Pyro-glutamic acid truncated amyloid beta 3-40/42 may have a greater propensity to aggregate under physiological conditions. In addition, this pyro E modification has been implicated as the molecular species responsible for seeding larger oligomers of amyloid-β. Pyro-glutamic acid truncated amyloid beta 3-40/42’s exact involvement in the pathophysiology of Alzheimer’s disease has not been established.1) Schilling S, Lauber T, Schaupp M, Manhart S, Scheel E, Bohm G, Demuth HU. On the seeding and oligomerization of pGlu-amyloid peptides (in vitro). Biochemistry. 2006 Oct 17;45(41):12393-9
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Immunogen
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A synthetic peptide corresponding to the N-terminus 3-pyro E start point.
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Amyloid-Beta 3 AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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ELISAIHCWB
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ELISA , Western (immuno) blotting (in testing), Immunostaining (in testing):
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Species Reactivity
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BovineHumanHumanSheep
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Amyloid-Beta 3 AntibodyTarget Information
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Gene Symbol
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APP
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Alternative Names
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Amyloid-Beta 3-pyr E
AAA
AD1
PN2
ABPP
APPI
CVAP
ABETA
PN-II
CTFgamma
A4
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Tissue Specificity
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Will not react to rodentia.
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Amyloid-Beta 3 AntibodyDatabase Links
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Entrez Gene
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351
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Protein Accession
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P05067
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Amyloid-Beta 3 AntibodyApplication
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Application Notes
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ELISA , Western (immuno) blotting (in testing), Immunostaining (in testing):
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Additional Information
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Form
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Liquid
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Storage Instructions
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For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.
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Storage Buffer
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phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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