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產(chǎn)品名稱: Amyloid-Beta 11 Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Amyloid-Beta 11 Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Amyloid-Beta 11 Antibody嚴格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細胞**熒光、**組化、流式細胞術(shù)、ELISA、CHIP、IP和peptide array。
Amyloid-Beta 11 Antibody
的詳細介紹
Amyloid-Beta 11 AntibodyProduct Profile
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Product Name
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Amyloid-Beta 11 Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Pyroglutamic acid truncated amyloid beta 11-40/42 may have a greater propensity to aggregate under physiological conditions. In addition, this pyrE modification has been implicated as the molecular species responsible for seeding larger oligomers of amyloid-β. Pyroglutamic acid truncated amyloid beta 11-40/42’s exact involvement in the pathophysiology of Alzheimer’s disease has not been established1) Schilling S, Lauber T, Schaupp M, Manhart S, Scheel E, Bohm G, Demuth HU. On the seeding and oligomerization of pGlu-amyloid peptides (in vitro). Biochemistry. 2006 Oct 17;45(41):12393-9
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Immunogen
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A synthetic peptide corresponding to the N-terminus 11-pyro E start point.
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Amyloid-Beta 11 AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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ELISAIHCWB
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ELISA , Western (immuno) blotting (in testing), Immunostaining (in testing):
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Species Reactivity
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Human
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Amyloid-Beta 11 AntibodyTarget Information
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Gene Symbol
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APP
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Alternative Names
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Amyloid-Beta 11-pyrE
AAA
AD1
PN2
ABPP
APPI
CVAP
ABETA
PN-II
CTFgamma
A4
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Amyloid-Beta 11 AntibodyDatabase Links
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Entrez Gene
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351
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Protein Accession
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P05067
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Amyloid-Beta 11 AntibodyApplication
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Application Notes
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ELISA , Western (immuno) blotting (in testing), Immunostaining (in testing):
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Additional Information
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Form
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Liquid
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Storage Instructions
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For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.
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Storage Buffer
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phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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