MAPK1/3 (phospho Tyr205/222) Antibody
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產(chǎn)品名稱: MAPK1/3 (phospho Tyr205/222) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
MAPK1/3 (phospho Tyr205/222) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。MAPK1/3 (phospho Tyr205/222) Antibody嚴格的質(zhì)量控制和驗證實驗包括各種不同的應用：WB、細胞**熒光、**組化、流式細胞術(shù)、ELISA、CHIP、IP和peptide array。
MAPK1/3 (phospho Tyr205/222) Antibody
的詳細介紹
MAPK1/3 (phospho Tyr205/222) AntibodyProduct Profile
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Product Name
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MAPK1/3 (phospho Tyr205/222) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.1) Owaki H., Biochem. Biophys. Res. Commun. 182:1416-1422(1992).
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Immunogen
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MAPK1/3 (phospho Tyr205/222) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 205/222 (K-G-Y (p)-T-K) derived from Human MAPK1/3 .
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MAPK1/3 (phospho Tyr205/222) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Western Blot: 1:500~1:1000:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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MAPK1/3 (phospho Tyr205/222) AntibodyTarget Information
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Gene Symbol
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MAPK1, MAPK3
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Alternative Names
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ERK
ERT1
MAPK 1
MAPK2
ERK2
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Molecular Weight(MW)
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44 kDa
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Tissue Specificity
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The antibody detects endogenous levels of MAPK1/3 only when phosphorylated at tyrosine 205/222.
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MAPK1/3 (phospho Tyr205/222) AntibodyDatabase Links
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Entrez Gene
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5594/5595
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Protein Accession
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NP_002736.3
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MAPK1/3 (phospho Tyr205/222) AntibodyApplication
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Application
Western blot analysis of extracts from JK cells using MAPK1/3 (Phospho-Tyr205/222) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Application Notes
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Western Blot: 1:500~1:1000:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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