FGFR1/2 (phospho Tyr463/466) Antibody
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產(chǎn)品名稱: FGFR1/2 (phospho Tyr463/466) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
FGFR1/2 (phospho Tyr463/466) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。FGFR1/2 (phospho Tyr463/466) Antibody嚴格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細胞**熒光、**組化、流式細胞術(shù)、ELISA、CHIP、IP和peptide array。
FGFR1/2 (phospho Tyr463/466) Antibody
的詳細介紹
FGFR1/2 (phospho Tyr463/466) AntibodyProduct Profile
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Product Name
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FGFR1/2 (phospho Tyr463/466) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.1) Itoh N., Biochem. Biophys. Res. Commun. 169:680-685(1990).
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Immunogen
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FGFR1/2 (phospho Tyr463/466) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 463/466 (S-E-Y (p)-E-L) derived from Human FGFR1/2.
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FGFR1/2 (phospho Tyr463/466) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Species Reactivity
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HumanMouse
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Concentration
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1mg/ml
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Purification
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Affinity purified
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FGFR1/2 (phospho Tyr463/466) AntibodyTarget Information
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Gene Symbol
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FGFR1, FGFR2
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Alternative Names
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BFGFR
CEK
FLG
CD331
FLT2
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Molecular Weight(MW)
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91 kDa
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Tissue Specificity
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The antibody detects endogenous levels of FGFR1/2 only when phosphorylated at tyrosine 463/466.
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FGFR1/2 (phospho Tyr463/466) AntibodyDatabase Links
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Entrez Gene
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2260/2263
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Protein Accession
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NP_075598.2
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FGFR1/2 (phospho Tyr463/466) AntibodyApplication
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Application
Western blot analysis of extracts from HepG2 cells using FGFR1/2 (Phospho-Tyr463/466) Antibody. The lane on the right is treated with the antigen-specific peptide.
Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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