MEK1 / MEK2 (phospho Ser217 / Ser221) Antibody
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產(chǎn)品名稱: MEK1 / MEK2 (phospho Ser217 / Ser221) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
MEK1 / MEK2 (phospho Ser217 / Ser221) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。MEK1 / MEK2 (phospho Ser217 / Ser221) Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
MEK1 / MEK2 (phospho Ser217 / Ser221) Antibody
的詳細(xì)介紹
MEK1 / MEK2 (phospho Ser217 / Ser221) AntibodyProduct Profile
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Product Name
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MEK1 / MEK2 (phospho Ser217 / Ser221) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.1) Shen R, et al. (2002) Mol Cell Biol; 22 (10): 3230-3236Preisinger C, et al. (2005) EMBO J; 24 (4): 753-765Laine P, et al. (2000) Biochem J; 349 (Pt 1): 19-25Yaglom J, et al. (2003) Mol Cell Biol; 23 (11): 3813-3824Dahan S, et al. (2002) Infect Immun; 70 (5): 2304-2310
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Immunogen
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MEK1/MEK2 (Phospho-Ser217/Ser221) antibody was raised against a peptide sequence around phosphorylation site of serine 217/221 (I-D-S (p) -M-A) derived from Human MEK1/MEK2.
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MEK1 / MEK2 (phospho Ser217 / Ser221) AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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IHCWB
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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MEK1 / MEK2 (phospho Ser217 / Ser221) AntibodyTarget Information
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Gene Symbol
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MAP2K1 MAP2K2
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Alternative Names
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CFC3
MEK1
MKK1
MAPKK1
PRKMK1
ERK activator kinase 1/ERK activator kinase2
MAP kinase kinase 1/MAP kinase kinase 2
MAP2K1/MAP2K1
MAPK/ERK kinase 1/MAPK/ERK kinase 2
MAPKK 1/MAPKK 1
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Molecular Weight(MW)
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45 kDa
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Tissue Specificity
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This antibody detects endogenous level ofMEK1/MEK2 only when phosphorylated at serine 217/221.
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MEK1 / MEK2 (phospho Ser217 / Ser221) AntibodyDatabase Links
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Entrez Gene
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5604 / 5605
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Protein Accession
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NP_002746.1 / NP_109587.1
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MEK1 / MEK2 (phospho Ser217 / Ser221) AntibodyApplication
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Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MEK1/MEK2 (Phospho-Ser217/Ser221).
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Application
Western blot analysis of lysed extracts from HeLa cell untreated or treated with UV MEK1/MEK2 (Phospho-Ser217/Ser221) Antibody#11205
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Application Notes
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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