SYK (phospho Tyr352) Antibody
如果您對該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: SYK (phospho Tyr352) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關文檔
簡單介紹
SYK (phospho Tyr352) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。SYK (phospho Tyr352) Antibody嚴格的質量控制和驗證實驗包括各種不同的應用：WB、細胞**熒光、**組化、流式細胞術、ELISA、CHIP、IP和peptide array。
SYK (phospho Tyr352) Antibody
的詳細介紹
SYK (phospho Tyr352) AntibodyProduct Profile
|
Product Name
|
SYK (phospho Tyr352) Antibody
|
|
Antibody Type
|
Primary Antibodies
|
|
Product description
|
Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion1) Yagi S., Biochem. Biophys. Res. Commun. 200:28-34(1994).
More
|
|
Immunogen
|
SYK (phospho Tyr352) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 352 (S-P-Y (p)-A-D) derived from Human SYK.
|
SYK (phospho Tyr352) AntibodyKey Feature
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Host Species
|
Rabbit
|
|
Tested Applications
|
WB
|
|
|
Western Blot: 1:500~1:1000:
|
|
Species Reactivity
|
HumanMouseRat
|
|
Concentration
|
1mg/ml
|
|
Purification
|
Affinity purified
|
SYK (phospho Tyr352) AntibodyTarget Information
|
Gene Symbol
|
SYK
|
|
Alternative Names
|
SYK
KSYK
FLJ25043
FLJ37489
More
|
|
Molecular Weight(MW)
|
72 kDa
|
|
Tissue Specificity
|
The antibody detects endogenous levels of SYK only when phosphorylated at tyrosine 352.
|
SYK (phospho Tyr352) AntibodyDatabase Links
|
Entrez Gene
|
6850
|
|
Protein Accession
|
NP_001167638.1
|
SYK (phospho Tyr352) AntibodyApplication
-
Application
Western blot analysis of extracts from HuvEc cells (Lane 2) and HepG2 cells (Lane 3), using SYK (Phospho-Tyr352) Antibody. The lane on the left is treated with antigen-specific peptide.
|
Application Notes
|
Western Blot: 1:500~1:1000:
|
Additional Information
|
Form
|
Liquid
|
|
Storage Instructions
|
Store antibody at -20?C for up to one year.
|
|
Storage Buffer
|
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
|
