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產(chǎn)品資料

CCND1-Y226 Antibody

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產(chǎn)品名稱: CCND1-Y226 Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔

簡單介紹

CCND1-Y226 Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。CCND1-Y226 Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用:WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。


CCND1-Y226 Antibody  的詳細(xì)介紹

CCND1-Y226 AntibodyProduct Profile

Product Name CCND1-Y226 Antibody
Antibody Type Primary Antibodies
Product description
					
CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb.1) Edel, M.J., et al. Genes Dev. 24(6):561-573(2010)
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Immunogen
This CCND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-238 amino acids from human CCND1.

CCND1-Y226 AntibodyKey Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

IFWB

For WB starting dilution is: 1:1000 For IF starting dilution is: 1:10~50:
Species Reactivity

Human

Concentration 1mg/ml
Purification Affinity purified

CCND1-Y226 AntibodyTarget Information

Gene Symbol CCND1
Alternative Names
G1/S-specific cyclin-D1
B-cell lymphoma 1 protein
BCL-1
BCL-1 oncogene
PRAD1 oncogene
CCND1
BCL1
PRAD1
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Molecular Weight(MW) 34 kDa

CCND1-Y226 AntibodyDatabase Links

Entrez Gene 595
Protein Accession P24385

CCND1-Y226 AntibodyApplication

  • Application

    Confocal immunofluorescent analysis of CCND1-Y226 Antibody with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).

  • Application

    Western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstratesdetected the CCND1 protein (arrow).

Application Notes
For WB starting dilution is: 1:1000 For IF starting dilution is: 1:10~50:

Additional Information

Form Liquid
Storage Instructions Store at 4?C for three months and -20?C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.

滬公網(wǎng)安備 31011702004356號

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