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產(chǎn)品資料

HSF1 Sumoylation Site Antibody

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產(chǎn)品名稱: HSF1 Sumoylation Site Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關文檔

簡單介紹

HSF1 Sumoylation Site Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。HSF1 Sumoylation Site Antibody嚴格的質(zhì)量控制和驗證實驗包括各種不同的應用:WB、細胞**熒光、**組化、流式細胞術(shù)、ELISA、CHIP、IP和peptide array。


HSF1 Sumoylation Site Antibody  的詳細介紹

HSF1 Sumoylation Site AntibodyProduct Profile

Product Name HSF1 Sumoylation Site Antibody
Antibody Type Primary Antibodies
Product description
					
Heat shock transcription factor 1 (HSF1) mediates the induction of heat shock protein gene expression in cells exposed to elevated temperature and other stress conditions. In response to stress, HSF1 acquires DNA-binding ability and localizes to nuclear stress granules. SUMO modification of HSF1 converts HSF1 to the DNA-binding form. HSF1 colocalizes with SUMO-1 in nuclear stress granules, which is prevented by mutation of the HSF1 lysine targeted for sumoylation.1) Hilgarth, et al., Biochem Biophys Res Commun. 2003 Mar 28;303(1):196-200.
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Immunogen
This HSF1 Sumoylation Site antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-309 amino acids from human HSF1 Sumoylation Site.

HSF1 Sumoylation Site AntibodyKey Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

IFWB

For WB starting dilution is: 1:1000 For IF starting dilution is: 1:10~50:
Species Reactivity

HumanMouse

Concentration 1mg/ml
Purification Unpurified

HSF1 Sumoylation Site AntibodyTarget Information

Gene Symbol HSF1
Alternative Names
Heat shock factor protein 1
HSF 1
Heat shock transcription factor 1
HSTF 1
HSF1
HSTF1
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Molecular Weight(MW) 57 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Bovine

HSF1 Sumoylation Site AntibodyDatabase Links

Entrez Gene 3297
Protein Accession Q00613

HSF1 Sumoylation Site AntibodyApplication

  • Application

    Western blot analysis in Jurkat cell line and mouse heart tissue lysates (35ug/lane).

  • Application

    Confocal immunofluorescent analysis of HSF1 Sumoylation Site Antibody with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Application Notes
For WB starting dilution is: 1:1000 For IF starting dilution is: 1:10~50:

Additional Information

Form Liquid
Storage Instructions Store at 4?C for three months and -20?C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.

滬公網(wǎng)安備 31011702004356號

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