Bax (phospho Thr167) Antibody
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產(chǎn)品名稱: Bax (phospho Thr167) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Bax (phospho Thr167) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動(dòng)劑/拮抗劑/活化劑/抑制劑及裂解物等。Bax (phospho Thr167) Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
Bax (phospho Thr167) Antibody
的詳細(xì)介紹
Bax (phospho Thr167) AntibodyProduct Profile
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Product Name
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Bax (phospho Thr167) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.1) Francesca Andriani. J Natl Cancer Inst, Sep 2001; 93: 1314 - 1324.
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Immunogen
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Bax (phospho Thr167) antibody was raised against a peptide sequence around phosphorylation site of threonine167 (P-G-T (p)-P-T) derived from Human Bax.
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Bax (phospho Thr167) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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IF
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Bax (phospho Thr167) AntibodyTarget Information
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Gene Symbol
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BAX
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Alternative Names
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BAXA
Apoptosis regulator BAX
membrane isoform alpha
Bcl2-associated X protein
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Molecular Weight(MW)
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21 kDa
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Tissue Specificity
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The antibody detects endogenous levels of Bax only when phosphorylated at threonine 167.
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Bax (phospho Thr167) AntibodyDatabase Links
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Entrez Gene
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581
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Protein Accession
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NP_620116.1
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Bax (phospho Thr167) AntibodyApplication
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Application
Immunofluorescence staining of methanol-fixed A549 cells using Bax (Phospho-Thr167) Antibody.
Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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