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產(chǎn)品名稱: Mouse Abl1 Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Mouse Abl1 Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Mouse Abl1 Antibody嚴(yán)格的質(zhì)量控制和驗(yàn)證實(shí)驗(yàn)包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
Mouse Abl1 Antibody
的詳細(xì)介紹
Mouse Abl1 AntibodyProduct Profile
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Product Name
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Mouse Abl1 Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.1) Ko, H.S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(38):16691-16696(2010)
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Immunogen
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This Mouse Abl1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-641 amino acids from the Central region of mouse Abl1.
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Mouse Abl1 AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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Ig
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Host Species
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Rabbit
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Tested Applications
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IHC-PWB
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For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
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Species Reactivity
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Mouse
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Mouse Abl1 AntibodyTarget Information
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Gene Symbol
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Abl1
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Alternative Names
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Tyrosine-protein kinase ABL1
Abelson murine leukemia viral oncogene homolog 1
Abelson tyrosine-protein kinase 1
Proto-oncogene c-Abl
p150
Abl1
Abl
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Molecular Weight(MW)
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123 kDa
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Mouse Abl1 AntibodyDatabase Links
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Entrez Gene
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11350
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Protein Accession
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P00520
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Mouse Abl1 AntibodyApplication
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Application
Mouse Abl1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse duodenum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Application
Western blot analysis in mouse spleen tissue lysates (35ug/lane).
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Application Notes
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For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store at 4?C for three months and -20?C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Storage Buffer
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Supplied in PBS with 0.09% (W/V) sodium azide.
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