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產(chǎn)品資料

TrkA (phospho Ser791) Antibody

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產(chǎn)品名稱: TrkA (phospho Ser791) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔

簡單介紹

TrkA (phospho Ser791) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。TrkA (phospho Ser791) Antibody嚴格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用:WB、細胞**熒光、**組化、流式細胞術(shù)、ELISA、CHIP、IP和peptide array。


TrkA (phospho Ser791) Antibody  的詳細介紹

TrkA (phospho Ser791) AntibodyProduct Profile

Product Name TrkA (phospho Ser791) Antibody
Antibody Type Primary Antibodies
Product description
					
Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC γ1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC γ1-dependent signaling pathway.1) Wiese S, et al. Proc Natl Acad Sci U S A. 2007 Oct 23; 104 (43): 17210-5. Valdez G, et al. Proc Natl Acad Sci U S A. 2007 Jul 24;104 (30): 12270-5Inoue K, et al. J Biol Chem. 2007 Aug 17;282 (33): 24175-84
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Immunogen
TrkA (Phospho-Ser791) antibody was raised against a peptide sequence around phosphorylation site of tyrosine791 (P-V-Y (p) -L-D) derived from Human TrkA.

TrkA (phospho Ser791) AntibodyKey Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IFWB

Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200:
Species Reactivity

Human

Concentration 1mg/ml
Purification Affinity purified

TrkA (phospho Ser791) AntibodyTarget Information

Gene Symbol NTRK1
Alternative Names
MTC
TRK
TRK1
TRKA
Trk-A
p140-TrkA
MGF
SCF
High affinity nerve growth factor receptor precursor
NTRK1
Slow nerve growth factor receptor
TRK1 transforming tyrosine kinase protein
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Molecular Weight(MW) 140 kDa
Tissue Specificity This antibody detects endogenous level of TrkA only when phosphorylated at tyrosine 791.

TrkA (phospho Ser791) AntibodyDatabase Links

Entrez Gene 4914
Protein Accession NP_001007793.1

TrkA (phospho Ser791) AntibodyApplication

  • Application

    Western blot analysis of lysed extracts from Rat and Mouse brain tissue using TrkA (Phospho-Ser791).

  • Application

    Immunofluorescence staining of methanol-fixed HeLa cells using TrkA (Phospho-Ser791).

Application Notes
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20?C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

滬公網(wǎng)安備 31011702004356號

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