Ezrin (phospho Tyr146) Antibody
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產(chǎn)品名稱: Ezrin (phospho Tyr146) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關文檔
簡單介紹
Ezrin (phospho Tyr146) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Ezrin (phospho Tyr146) Antibody嚴格的質(zhì)量控制和驗證實驗包括各種不同的應用：WB、細胞**熒光、**組化、流式細胞術、ELISA、CHIP、IP和peptide array。
Ezrin (phospho Tyr146) Antibody
的詳細介紹
Ezrin (phospho Tyr146) AntibodyProduct Profile
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Product Name
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Ezrin (phospho Tyr146) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.1) Murchie R, et al. (2014)Proc Natl Acad Sci U S A 111, 693-8. Kawahara T, et al. (2013)PLoS One 8, e79654 . Wang Y, Lazo JS (2012)Oncogene 31, 818-27.
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Immunogen
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Ezrin (phospho Tyr146) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 146 (S-G-Y (p)-L-S) derived from Human Ezrin.
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Ezrin (phospho Tyr146) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Western Blot: 1:500~1:1000:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Ezrin (phospho Tyr146) AntibodyTarget Information
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Gene Symbol
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EZR
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Alternative Names
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Cytovillin
EZRI
p81
VIL2
Villin 2
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Molecular Weight(MW)
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69 kDa
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Tissue Specificity
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The antibody detects endogenous level of Ezrin only when phosphorylated at tyrosine 146.
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Ezrin (phospho Tyr146) AntibodyDatabase Links
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Entrez Gene
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7430
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Protein Accession
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NP_001104547.1
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Ezrin (phospho Tyr146) AntibodyApplication
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Application
Western blot analysis of extracts from 293 cells treated with UV using Phospho-Ezrin (Tyr146) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Application Notes
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Western Blot: 1:500~1:1000:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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