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產(chǎn)品名稱: Mouse Irak1 Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關文檔
簡單介紹
Mouse Irak1 Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Mouse Irak1 Antibody嚴格的質(zhì)量控制和驗證實驗包括各種不同的應用：WB、細胞**熒光、**組化、流式細胞術、ELISA、CHIP、IP和peptide array。
Mouse Irak1 Antibody
的詳細介紹
Mouse Irak1 AntibodyProduct Profile
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Product Name
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Mouse Irak1 Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Irak1 binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. The kinase activity of this enzyme may not be required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.1) Vaughan, T., et al. Mol. Immunol. 47(15):2515-2518(2010)
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Immunogen
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This Mouse Irak1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-433 amino acids from the Central region of mouse Irak1.
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Mouse Irak1 AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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Ig
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Host Species
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Rabbit
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Tested Applications
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FACSWB
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For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50:
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Species Reactivity
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Mouse
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Mouse Irak1 AntibodyTarget Information
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Gene Symbol
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Irak1
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Alternative Names
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Interleukin-1 receptor-associated kinase 1
IRAK
IRAK-1
Pelle-like protein kinase
mPLK
Irak1
Il1rak
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Molecular Weight(MW)
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77 kDa
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Mouse Irak1 AntibodyDatabase Links
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Entrez Gene
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16179
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Protein Accession
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Q62406
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Mouse Irak1 AntibodyApplication
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Application
Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).
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Application
Flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
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Application Notes
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For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store at 4?C for three months and -20?C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Storage Buffer
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Supplied in PBS with 0.09% (W/V) sodium azide.
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