如果您對該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: Mouse Irak1 Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Mouse Irak1 Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Mouse Irak1 Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細胞**熒光、**組化、流式細胞術(shù)、ELISA、CHIP、IP和peptide array。
Mouse Irak1 Antibody
的詳細介紹
Mouse Irak1 AntibodyProduct Profile
|
Product Name
|
Mouse Irak1 Antibody
|
|
Antibody Type
|
Primary Antibodies
|
|
Product description
|
Irak1 binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. The kinase activity of this enzyme may not be required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.1) Vaughan, T., et al. Mol. Immunol. 47(15):2515-2518(2010)
More
|
|
Immunogen
|
This Mouse Irak1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-433 amino acids from the Central region of mouse Irak1.
|
Mouse Irak1 AntibodyKey Feature
|
Clonality
|
Polyclonal
|
|
Isotype
|
Ig
|
|
Host Species
|
Rabbit
|
|
Tested Applications
|
FACSWB
|
|
|
For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50:
|
|
Species Reactivity
|
Mouse
|
|
Concentration
|
1mg/ml
|
|
Purification
|
Affinity purified
|
Mouse Irak1 AntibodyTarget Information
|
Gene Symbol
|
Irak1
|
|
Alternative Names
|
Interleukin-1 receptor-associated kinase 1
IRAK
IRAK-1
Pelle-like protein kinase
mPLK
Irak1
Il1rak
More
|
|
Molecular Weight(MW)
|
77 kDa
|
Mouse Irak1 AntibodyDatabase Links
|
Entrez Gene
|
16179
|
|
Protein Accession
|
Q62406
|
Mouse Irak1 AntibodyApplication
-
Application
Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).
-
Application
Flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
|
Application Notes
|
For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50:
|
Additional Information
|
Form
|
Liquid
|
|
Storage Instructions
|
Store at 4?C for three months and -20?C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
|
|
Storage Buffer
|
Supplied in PBS with 0.09% (W/V) sodium azide.
|
