STAT3 (phospho Ser727) Antibody
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產(chǎn)品名稱: STAT3 (phospho Ser727) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
STAT3 (phospho Ser727) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。STAT3 (phospho Ser727) Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細胞**熒光、**組化、流式細胞術(shù)、ELISA、CHIP、IP和peptide array。
STAT3 (phospho Ser727) Antibody
的詳細介紹
STAT3 (phospho Ser727) AntibodyProduct Profile
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Product Name
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STAT3 (phospho Ser727) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.1) Heim M H, (1999) J Recept Signal Transduct Res. 19: 75-120. Takeda K, et al. (1997) Proc Natl Acad Sci USA. 94: 3801-3804. Catlett-Falcone R, et al. (1999) Immunity. 10: 105-115. Garcia R, et al. (1998) J Biomed Sci. 5: 79-85. Bromberg J F, et al. (1999) Cell. 98: 295-303.
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Immunogen
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STAT3 (Phospho-Ser727) antibody was raised against a peptide sequence around phosphorylation site of serine 727 (P-M-S (p) -P-R) derived from Human STAT3.
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STAT3 (phospho Ser727) AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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IFIHCWB
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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STAT3 (phospho Ser727) AntibodyTarget Information
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Gene Symbol
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STAT3
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Alternative Names
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APRF
HIES
STAT5
APRF
Acute-phase response factor
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Molecular Weight(MW)
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88 kDa
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Tissue Specificity
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This antibody detects endogenous level of STAT3 only when phosphorylated at serine 727.
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STAT3 (phospho Ser727) AntibodyDatabase Links
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Entrez Gene
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6774
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Protein Accession
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NP_003141.2
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STAT3 (phospho Ser727) AntibodyApplication
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Application
Western blot analysis of lysed extracts from HeLa and HepG2 cells untreated or treated with PMA using STAT3 (Phospho-Ser727).
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Application
Top Image: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT3 (Phospho-Ser727). Bottom Image: Immunofluorescence staining of methanol-fixed HeLa cells using STAT3 (Phospho-Ser727).
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Application Notes
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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